Fritz E. Kühn

Synthesis, Cytotoxicity, and Mechanistic Evaluation of Thiazolium-Based Gold(I) Bis- N -Heterocyclic Carbene Complexes

Abstract Imidazole- and benzimidazole-based Au(I) N-heterocyclic carbene (NHC) complexes show great potency as anticancer agents. However, other NHC scaffolds are only sparsely explored. Four gold(I) NHC complexes featuring thiazolium-based ligands (NHCthia) with varying N-substi...