Frederick A. Luzzio

Copper(II)/TBHP-mediated oxidation of isoindolinones and other substrates—effect of air and oxygen

When employed in conjunction with tert-butyl hydroperoxide (TBHP), iron(III) and copper(II)-catalyzed oxidation systems have proven to be effective in transforming isoindolinones to the corresponding phthalimides. Considering both metal-mediated processes, one of the issues that...