Frédéric Affouard

Molecular mechanisms of supercritical CO2-induced interfacial softening in curcumin polymorphs

Unique properties of supercritical CO 2 (scCO 2 ) make it one of the most interesting “green” solvents for pharmaceutical particle formation and polymorph engineering. However, due to the complexity of the scCO 2 dynamics, the molecular mechanisms by which scCO 2 alters the stabi...