Francisco José Parrilla-Gómez

Prediction of high-flow nasal cannula failure in COVID-19 acute hypoxemic respiratory failure using combined clinical and metabolomic data: a machine learning study

Background High-flow nasal cannula (HFNC) is widely used as first-line non-invasive respiratory support in acute hypoxemic respiratory failure (AHRF), particularly during the COVID-19 pandemic. However, HFNC failure remains frequent, and delayed intubation is associated with wors...