Francesco Santarella

Aggressive PK/PD Target Attainment With Beta-lactams in critically Ill Pediatric Patients Having Suspected or Documented Gram-negative Infections—Prevalence, Risk Factors of Nonattainment and Impact on Clinical Outcome

Objective: To perform a systematic review with meta-analysis for evaluating the prevalence of aggressive beta-lactams pharmacokinetic/pharmacodynamic (PK/PD) target attainment, identifying predictors of aggressive PK/PD target nonattainment, and assessing the impact of attaining...