Fereshte Hossein

Context-dependent interactions between immune checkpoint and epithelial-mesenchymal transition programs shape the tumor microenvironment in esophageal squamous cell carcinoma

Abstract Background Immune checkpoint (ICP) and epithelial-mesenchymal transition (EMT) pathways are key biological processes implicated in the progression of esophageal squamous cell carcinoma (ESCC). However, their transcriptional interplay and interactions with the tumor immun...