Feng Zhang

A novel ATP7A splice‑site variant with suspected maternal gonadal mosaicism in Menkes disease: functional validation and prenatal diagnosis

Abstract Menkes disease (MIM#309400) is a rare, fatal X-linked neurodegenerative disorder caused by ATP7A mutations. Delayed diagnosis due to clinical heterogeneity and limited data on mutational spectrum and reproductive risk remain challenges, with gonadal mosaicism being an of...

Polyendocrine metabolic ovarian syndrome (PMOS, formerly Polycystic Ovary Syndrome): a systems-biology perspective on neuroendocrine, immuno-metabolic and epigenetic mechanisms across the life course

Polyendocrine metabolic ovarian syndrome (PMOS) is the name adopted in 2026 by the Global Name Change Consortium for the condition previously called polycystic ovary syndrome (PCOS); diagnostic criteria are unchanged, and a managed three-year transition to the new terminology is...

Catalytic Shunt for Sustainable Photosynthesis of Hydrogen Peroxide from Hypersaline Organic Wastewater

Abstract Photosynthetic hydrogen peroxide (H2O2) production from organic wastewater offers a sustainable alternative to the energy-intensive anthraquinone process, yet it is severely hindered by rapid quenching of reactive precursors by concentrated salts in hypersaline organic w...