Feng Du

Collagen-targeted extracellular vesicles from exercised progenitors restore cardiac microcirculation via endothelial AMPK-eNOS-NO axis reactivation

Endothelial dysfunction, driven by impairment of the AMPK-eNOS-NO signaling axis, is a primary defect in diabetic cardiomyopathy (DCM). Extracellular vesicles (EVs) are key mediators of intercellular communication. EVs from exercised conditions possess enhanced bioactivity, but t...