Author
Felix Bratosin
Recent research
- Health & MedicineOpen access
Background: Fosmanogepix is a first-in-class Gwt1 inhibitor with oral and intravenous formulations and broad in vitro activity, but its clinical evidence is scattered across small trials and case reports. We reviewed all identifiable human data from the searched sources on its ef...
- Health & MedicineOpen access
Olorofim, the first orotomide antifungal, is active against Aspergillus spp., Lomentospora prolificans, Scedosporium spp. and Coccidioides spp. We reviewed published clinical reports of olorofim in invasive fungal disease (IFD) with limited or no treatment options. PubMed/MEDLINE...
- Health & MedicineOpen access
Background and Objectives: Penile prosthesis infection usually ends in device removal, whereas unnecessarily broad or prolonged prophylaxis causes toxicity and promotes resistance. We assessed whether the systemic perioperative antibacterial or antifungal strategy, dose or durati...