Felix Benedikt Engel

Integrative Bioinformatics Across Proliferative and Non-Proliferative Cell States Reveals Novel Cytokinesis Genes

The mammalian heart has no significant endogenous regenerative capacity, as mammalian cardiomyocytes undergo a last round of cell cycle after birth, becoming post-mitotic and polyploid. Consistent with this, cytokinesis inhibition in zebrafish impairs their cardiac regenerative c...