Federica Barbato

“DNA damage activates cGAS-STING signaling through ROS dependent p62 recruitment”

Abstract Ionizing radiation (IR) induces DNA damage that activates innate immunity through the cyclic GMP–AMP synthase (cGAS) pathway, yet the mechanisms determining why only a subset of radiation-induced micronuclei (MNi) become cGAS-positive remain unclear. Here, we investigate...