Fatemeh Sameni

Targeting ferroptosis in cancer: molecular mechanisms and emerging therapeutic strategies

Ferroptosis, an iron-dependent form of regulated cell death characterized by the lethal accumulation of lipid peroxides, has emerged as a pivotal pathway in cancer biology and a promising therapeutic target. This review synthesizes the core molecular machinery governing ferroptos...

Global prevalence of colistin resistance, mcr gene variants, and sequence types in Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, and Stenotrophomonas maltophilia: a systematic review and meta-analysis

Abstract Background Due to the increasing prevalence of infections caused by multidrug-resistant (MDR) Gram-negative bacteria, colistin has become an important therapeutic option. However, the rapid emergence of resistance to this antimicrobial agent, mediated by mechanisms such...