Farren J. Isaacs

Systematic prioritization of candidate genes in camptothecin biosynthesis using multi‐omics and deep learning

Abstract Camptothecin (CPT), a plant‐derived monoterpene indole alkaloid first identified in Camptotheca acuminata , is a drug precursor widely used for cancer chemotherapeutics. However, the full set of genes responsible for CPT biosynthesis remains unclear, hindering efforts to...