Fan Xia

Nanopipette Sensing of APE1 Activity via Enzymatic Recycling and DNA Tetrahedron−Streptavidin Reporting: Profiling in Cancer Diagnostics, Oxidative Stress, and Cell Cycle

Abstract Apurinic/apyrimidinic endonuclease 1 (APE1) is a clinical biomarker whose small molecular size hinders direct detection by conventional nanopores (30 nm). Here, we report a nanopipette platform integrating APE1-driven enzymatic recycling amplification with DNA tetrahedro...

Outer Surface Functionalized Graphene Oxide Nanofluidic Platform for Selective Detection of Insect Pheromones

Abstract Invasive insects inflict severe ecological and economic damage, creating an urgent need for rapid and early detection strategies. Here, we present a biomimetic strategy that replicates the molecular recognition principles of insect olfaction. As a proof of concept, our p...