Falk Hoffmann

Agranulocytosis associated with metamizole among EudraVigilance reports involving methotrexate for rheumatoid arthritis

Methotrexate (MTX) can induce adverse drug reactions (ADRs) including severe haematotoxic events. This study analyses whether agranulocytosis is disproportionately reported in spontaneous reports involving MTX for rheumatoid arthritis (RA) when use of metamizole, a non-opioid ana...

Delirium superimposed on dementia in nursing homes: prevalence, incidence, and prognosis – protocol of a prospective multicenter cohort study

Abstract Background Delirium is a frequent and serious neuropsychiatric syndrome in older adults. People living with dementia are at particularly high risk of developing delirium. In nursing homes, where dementia prevalence is high, delirium superimposed on dementia (DSD) represe...