Fabrizio De Massis

Brucella abortus RB51 vaccination: a comprehensive systematic review of safety, efficacy, and global field outcomes (1990–2025)

Brucella abortus strain RB51 is a live attenuated rough vaccine developed to overcome the serological interference of conventional smooth vaccines. Since replacing strain S19 in the United States (1996) and globally thereafter, RB51 has been promoted as a DIVA (Differentiating In...