Fabienne Ramona Caldana

Small Activating RNAs: A Curated Database and an Overview of Rational Design Principles

RNA activation (RNAa), mediated by small activating RNAs (saRNAs), upregulates endogenous gene expression through recruitment of the Argonaute proteins to the promoter, natural antisense transcripts, or other noncoding RNAs. This mechanistically distinct modality addresses an unm...