Evangelos Vassos

Genetic evidence for the psychosis continuum: polygenic score analysis

Background The psychosis continuum conceptualises psychotic phenomena as existing on a spectrum from subclinical experiences to psychotic disorders. Despite epidemiological and clinical evidence in support of this model, few studies have examined polygenic liability across the se...

22. STABLE SYMPTOM DEPRESSION SUBTYPES WITH DISTINCT GENETIC AND HEALTH SIGNATURES

Background Depression is a heterogeneous disorder, with individuals often showing diverse combinations of symptoms that may reflect distinct underlying biological mechanisms. Data driven approaches offer an opportunity to examine this heterogeneity and connect symptom profiles to...