Eva Forssell-Aronsson

Sex and age at exposure influence 131I biodistribution and dosimetry in Sprague–Dawley rats

Abstract Background Assessing the biodistribution and absorbed dose of ¹³¹I is crucial for optimisation of radionuclide therapy, as well as for improving risk assessment following nuclear emergencies. After the Chernobyl accident, an increase in thyroid cancer among children was...

Monte Carlo microdosimetry of 211at in multi-species thyroid follicle models: AlfaMC versus MCNPX and Geant4

Abstract Background Radionuclide therapy is an increasingly used treatment modality for patients with disseminated cancer diseases. Tumor-binding radiopharmaceuticals labelled with the alpha-particle emitter astatine-211 ( 211 At) are of interest to enable high radiation absorbed...