Esther Rey-Iborra

B7-H6 orchestrates oncogenic signaling and represents a therapeutic vulnerability in metastatic clear cell renal cell carcinoma

B7-H6 (NCR3LG1) is an immune checkpoint protein belonging to the B7 family of immunomodulatory proteins and serves as a ligand for the natural cytotoxicity triggering receptor NKp30 (NCR3) expressed on natural killer (NK) cells. In addition to its extracellular immunomodulatory d...