Eric S. Wohleb

Neuronal Ddit4 overexpression in the medial prefrontal cortex reduces synaptic density and impairs cognitive function in mice

Chronic stress exposure causes neurobiological and behavioral changes that resemble those reported in psychiatric conditions such as major depressive disorder (MDD). Preclinical stress models and studies using postmortem tissue from MDD patients have shown that DNA Damage-Inducib...