Enrico Catalano

Space Medicine and cardiovascular mathematical-computational simulation: Applications of Navier-Stokes Solutions to Astronaut Cardiovascular Systems

Prolonged human exposure to microgravity precipitates severe cardiovascular deconditioning driven by the elimination of hydrostatic pressure gradients. Gravitational unloading triggers an immediate cephalad fluid shift, progressive myocardial atrophy, spaceflight-associated neuro...

Advanced Mathematical Models, Biomathematics and Spatial Bioinformatics for the Discovery of Novel Therapeutic Targets

Rational therapeutic target discovery and systems biology face a decisive epistemological challenge: the fragmentation between the kinetic dynamics of intracellular pathways and the spatial-geometric complexity of macromolecular interactions. This work outlines an integrated anal...

Physical and Mathematical Modeling of the Cardiovascular System: An Overview of Aortic Hemodynamics, 3D Heart Simulation, and Fluid-Structure Interaction

A comprehensive overview of cardiovascular mathematics, a multidisciplinary field at the intersection of biomedical engineering, fluid dynamics, and computational mechanics is provided for analyzing multicomplex systems of blood circulation and the cardiovascular system. By trans...