Emily Matthews

Opioid antagonists for overdose reversal in the era of synthetic opioids: a scoping review of high-dose naloxone and nalmefene

Opioid overdose deaths in the United States have surged over the past two decades, driven largely by the proliferation of illicitly manufactured fentanyls (IMFs). Concerns that standard naloxone doses may be insufficient for reversing IMF-related overdoses have prompted FDA appro...