Emanuele Agolini

Establishment and characterization of primary retinoblastoma cell lines: a comprehensive molecular profiling approach

Retinoblastoma (RB) research is significantly constrained by the limited availability of preclinical models that accurately recapitulate the disease complexity, particularly regarding the context of vitreous seeding, a major driver of therapeutic resistance and treatment failure....

Genetic characterization of suspected hereditary melanoma in a Central Italy cohort

Approximately 5–12% of cutaneous melanomas arise in a familial context, suggesting hereditary predisposition. Our analysis aims to investigate the clinical and genetic background of melanoma patients living in the Lazio area with a personal and/or family history of melanoma or ot...