Eloise Mastrangelo

Structural dynamics and pH ‐regulated membrane binding of the TRAF2 ‐ NC trimer

Tumor necrosis factor receptor-associated factor 2 (TRAF2) is a key adaptor in TNF receptor-signaling that operates as a trimeric assembly. Here we investigate the structural and functional properties of a TRAF2 construct spanning the trimerization and receptor-binding domains (T...