Ellen Juel Pørtner

Surface Functionalization Modulates Collective Cell Behavior Near Topological Defects Induced by Topographical Patterning

ABSTRACT Living cells establish long‐range orientational order through collective alignment, giving rise to topological defects whose functional relevance is increasingly recognized in tissue organization and morphogenesis. Engineered topographical patterns have been used to indu...

Truncated ErbB2 receptor expression lowers nucleus stiffness and increases migration of breast cancer cells

The mechanisms underlying mechanical differences among cancer cell lines with varying metastatic potential remain poorly understood, despite their clear therapeutic relevance. While comparisons between malignant and benign cell mechanics reveal systematic differences, these are d...