Elisabetta Fontanini

Expression of Active Apurinic Apyrimidinic Endodeoxyribonuclease 1 in Human Platelets

ABSTRACT The pivotal role of platelets (PLTs) in hemostasis, thrombosis, innate immunity, and tissue repair is sustained by mitochondria, whose dysfunctions can impair ATP generation and redox signaling, thus affecting optimal levels of PLTs' functionality. Maintenance of mtDNA i...