Elisabeth Irran

Scrambling-free synthesis of heteroleptic silylium ions by halide abstraction from halosilanes

Abstract Heteroleptic silylium ions with different substituents at the silicon atom are generally not accessible using established tools for producing such reactive intermediates because substituent exchange reactions occur in acidic media, leading to homoleptic silylium ions wit...

Enantioselective Access to the Parent Helicenols by Kinetic Resolution through Cu–H-Catalyzed Si–O Coupling

Abstract A Cu–H-catalyzed kinetic resolution of the parent [n]helicenols (n = 5, 6) through enantioselective dehydrogenative silylation with a secondary silane is reported. The dihydrosilane eventually employed is prochiral, thereby simultaneously establishing stereogenicity at t...