Еlena V. Mitroshina

Cerebral dopamine neurotrophic factor (CDNF) affects hippocampal neuroplasticity and fear memory in rats

The role of CDNF in modulating learning and memory remains largely unexplored. Here, hippocampal CDNF overexpression significantly accelerated extinction of contextual and cued fear memory in rats. Molecularly, overexpressed CDNF was retained in the ER and upregulated mRNA levels...