Effrossyni Gkrania‐Klotsas

Large-scale GWAS meta-analysis of serum antibody levels in healthy individuals reveals distinct genetic architectures

Abstract Antibodies are the principal effector proteins of humoral immunity. Dysregulated antibody production is a feature of a number of heritable immune-mediated diseases, such as the antibody deficiencies and IgA nephropathy. To characterize the common-variant architecture of...