Edward L. Hurley

Schwann Cell‐Specific ATG7 ‐Dependent Autophagy Protects Myelin in a Mouse Model of Krabbe Disease

ABSTRACT Krabbe disease (KD) is a lysosomal storage disorder characterized by severe peripheral demyelination caused by mutations in galactosylceramidase (GALC), leading to the accumulation of galactosylceramide and psychosine. Although psychosine toxicity is central to KD pathol...