Edoardo Rolando

Integrative structural modelling reveals the human Mic60-Mic19 subcomplex as a diffusion barrier in mitochondria

Abstract Mitochondrial crista junctions (CJs) operate as regulated gateways into the cristae microenvironment, whose protein, metabolite, and ion compositions are finely tuned for mitochondrial function. The Mic60-Mic19 complex of the mitochondrial contact site and cristae organi...