Dustin R. Klein

Automated Electrostatic Attraction/Repulsion Hydrophilic Interaction Liquid Chromatography Screening for Polar and Charged Analytes in Complex Matrices

Abstract Electrostatic repulsion hydrophilic interaction liquid chromatography (ERLIC) provides unique selectivity for highly polar and charged analytes, yet method development remains challenging. Careful optimization of organic solvent gradients and buffer concentrations is ess...