Dongmiao Sang

Transcytosis-Guided Intestinal Absorption of Ultrasmall Gold Nanoparticles for Lymphatic Entry into Systemic Circulation

Abstract The intestinal epithelial barrier severely impedes absorption of orally administered nanoparticles. Herein, we designed ultrasmall PEPT1-targeted gold nanoparticles (GP-AuNPs) using a dual-ligand strategy: Gly-Sar peptides for PEPT1 recognition on intestinal epithelial c...