Donghua Hu

Circulating ANGPTL4 predicts CKD and ESKD risk: insights from large-scale proteomics and senescence mechanisms

Abstract Background The global burden of chronic kidney disease (CKD) is increasing significantly, with aging recognized as a major risk factor associated with accelerated biological aging and poor renal outcomes. Growing evidence links angiopoietin-like protein 4 (ANGPTL4) to bo...