Donghai Liang

Analysis of the Potential Mediating Role of Plasma Proteins in the Association Between Air Pollution Exposure and Lung Cancer Risk Among Ever-Smokers

Abstract The biological mechanisms linking air pollution to lung carcinogenesis remain underexplored. This study aimed to identify key proteins and pathways involved in mediating the effects of air pollutants on lung cancer risk. We analyzed 95 matched lung cancer case–control pa...

Associations Between Pre-diagnostic Plasma Metabolites and Ovarian Cancer: A Prospective Case-Cohort Analysis in the Cancer Prevention Study-3

BACKGROUND: Ovarian cancer remains a significant health concern among U.S. women, yet its underlying etiology is not fully understood. Untargeted metabolomics enables comprehensive profiling of small molecules that may provide insight into metabolic alterations associated with ov...

Prenatal exposure to wildfire fine particulate matter and fetal growth outcomes in the United States: Findings from the ECHO Cohort

Background: Increasing exposure to wildfire fine particulate matter (PM 2.5 ) may pose unique risks to fetal development. We assessed associations between prenatal wildfire PM 2.5 exposure and fetal growth outcomes, including birth weight at term, birth weight for gestational age...