Dieter Mayer

Severe, Therapy-Resistant Generalized Lichen Sclerosus with Morphea Overlap Successfully Treated with Intravenous Immunoglobulin and Type 1 Interferon Receptor Monoclonal Antibody Infusion: A Case Report

Introduction: Generalized extragenital lichen sclerosus with morphea overlap is a rare inflammatory and fibrosing dermatosis. Severe bullous-ulcerative disease remains therapeutically challenging and can cause major morbidity. Case Presentation: We report a 54-year-old woman with...

An update on biofilms in acute and chronic wounds: Incidence, clinical evidence, diagnosis, prevention, and treatment

Pathogenic biofilms are a critical barrier to wound healing, driving infection persistence, delayed tissue repair, and antimicrobial resistance (AMR) and tolerance. This recognition has driven a paradigm shift from a traditional planktonic model of infection to a biofilm-mediated...