Dianyu Liu

Novel mTORC1 Booster LAPTM4A Potentiates Pathological Cardiac Hypertrophy

BACKGROUND: Excessive unnecessary protein accumulation in cardiomyocyte is a leading contributor for pathological cardiac hypertrophy and has been found closely regulated by the mTORC1 (mechanistic target of rapamycin complex 1) signaling and lysosome transmembrane proteins. Howe...