Dianbin Ning

CSTF2 facilitates ATAD2 translation via m⁶A recognition to drive ER-positive breast cancer metabolic reprogramming and tumor progression

Abstract Objective Breast cancer (BC) is the most common malignancy among women worldwide, accounting for 11.7% of female cancer cases. Cleavage stimulation factor subunit 2 ( CSTF2 ), a key RNA-binding protein, modulates tumor development by influencing N⁶-methyladenosine (m⁶A)...