Devipriya M, Tulasiraja P K, Dr. S Hurmath Unnissa

In Silico Design and Computational Evaluation of Pyrazolo Cinnoline Analogs as Potential Phosphodiesterase Inhibitors for Breast Cancer

AbstractBreast cancer remains a major global health challenge due to its complex molecularmechanisms, therapeutic resistance, and limitations of existing treatments. Phosphodiesterase10A (PDE10A), a dual-specificity phosphodiesterase regulating intracellular cAMP and cGMPlevels,...