Desen Wang

A Microneedle Platform Co-loaded with Eugenol, Chlorogenic Acid, and Allopurinol for In Vivo Modulation of Pathological Crystal Formation in Experimental Gouty Arthritis

Abstract Gouty arthritis arises from pathological deposition of monosodium urate (MSU) crystals, whose interactions with surrounding tissues initiate and amplify inflammation. Here, we developed a nanoengineered microneedle (MN) platform for localized modulation of pathological c...

Spatiotemporally Controlled Double Self‐Emulsifying Microneedles for Co‐Delivery of Eugenol and Puerarin to Promote Healing and Tissue Regeneration of Infected Diabetic Wounds

Chronic infected diabetic foot ulcers (DFUs) pose a persistent challenge due to biofilm-shielded infections, excessive inflammation, and impaired tissue repair. Here, we present a first-in-class microneedle system that redefines eugenol (EUG), a natural compound, as a multifuncti...