Derek L. Osorio

Angiopoietin-Like 4 Induces Upregulation of VEGF and sVCAM1 Through JNK/c-Jun and JAK2/STAT5 Signaling Pathways

Purpose: Angiopoietin-like protein 4 (ANGPTL4) is a multifunctional cytokine regulating angiogenesis, vascular permeability, and inflammation that is elevated, along with vascular endothelial growth factor (VEGF), in multiple ocular neovascular disorders, including ischemic retin...