Deniz Bilecen

Dual Antifibrotic Modulation via CTGF Silencing and Peptide Amphiphile Nanofibers for Topical Treatment of Skin Fibrosis

Abstract Skin fibrosis is driven in part by transforming growth factor-β (TGF-β) signaling and the matricellular protein connective tissue growth factor (CTGF). Elevated CTGF expression is a hallmark of fibrotic skin lesions and contributes to pathological extracellular matrix re...