Denise Framke

Shear stress alters mito-cytoskeletal dynamics and mobilizes mechanosensitive transcription factors supporting a chemoresistant phenotype in ovarian cancer cells

Abstract Ovarian cancer remains one of the most lethal gynecological malignancies, largely due to the frequent development of resistance to platinum-based chemotherapies such as cisplatin (cisPt). Emerging evidence supports that the biophysical properties of the tumor microenviro...

Building a One Health mobile laboratory workforce: strengthening public health preparedness across Europe and Africa

Abstract The emergence and re-emergence of infectious diseases remain a major public health threat in Europe. The Horizon Europe-funded MOBILISE project addresses this challenge by establishing a One Health Mobile Laboratory capable of handling risk group 3 and 4 pathogens, while...