Demetrios G. Vavvas

Ambient light drives verteporfin-induced protein cross-linking during standard laboratory sample processing

Verteporfin (VP) is widely used as a light-independent pharmacologic inhibitor of the YAP-TEAD transcriptional complex, despite its potent photosensitizing properties. Here we show that VP-associated high–molecular–weight complexes and apparent depletion of key proteins on immuno...