Deividas Nekrošius

Altered contractile responses to angiotensin II and cholinergic stimulation in colonic circular smooth muscle from patients with diverticular disease

Background Abnormal circular smooth muscle contractility is considered a key factor in the pathogenesis of diverticular disease (DD), contributing to increased intraluminal pressure and diverticulum formation. Altered cholinergic responsiveness of colonic smooth muscle has previo...