Dehai Lang

Nicotinamide adenine dinucleotide phosphate hydrogen oxidase 2 exacerbates abdominal aortic aneurysm formation by inducing oxidative stress through autophagy inhibition.

, primary mouse vascular smooth muscle cells (VSMCs) were randomly divided into Control, AngII, AngII+GSK2795039, AngII+rapamycin (autophagy agonist, RA), and AngII+GSK2795039+RA groups. EDU assay, cell scratch assay, and mRFP-GFP-LC3 detection were conducted. ROS was measured by...