Dechang Peng

CT-derived spatial intratumoural heterogeneity and KRAS mutation status in a predominantly lung adenocarcinoma cohort: an exploratory study of association and incremental discrimination

Abstract Background To assess whether CT-derived spatial intratumoural heterogeneity (ITH) is associated with KRAS mutation status after accounting for tumour burden and clinical covariates, and whether it adds predictive information beyond clinical and volume-based reference mod...