Dean R. Tolan

AMP Deaminase-2 Activators and Regulators Underpinning Cellular Function in Human Fructose and Nucleotide Metabolism

Abstract AMP deaminase (AMPD) plays an integral role in fructose metabolism via its regulation by ATP, GTP, and phosphate (Pi). The fructose catabolic pathway consumes ATP, producing ADP, which is further metabolized to AMP, triggering a cascade of reactions initiated by AMPD. Th...