David Z. Rudner

Efficient septum formation is essential for chromosome segregation in Bacillus subtilis when SMC function is impaired

ABSTRACT Structural maintenance of chromosomes (SMC) complexes play conserved roles in chromosome organization, segregation, and repair in all domains of life. In Bacillus subtilis , SMC is required for the segregation of newly replicated origins. To investigate whether other pro...

Bacillus subtilis YpeB holds SleB inactive, preventing cortex peptidoglycan degradation during spore dormancy

ABSTRACT Bacterial endospores are encased in a thick layer of specialized peptidoglycan called the cortex that is essential for core dehydration and heat resistance. Spore germination and outgrowth require cortex degradation by enzymes that are deposited in the spore during sporu...